IsoPepTracker Documentation

Welcome to IsoPepTracker, an interactive peptide visualizer for alternative splicing analysis. It provides a comprehensive platform for analyzing peptides across protein isoforms, identifying novel peptides from alternative splicing events, and visualizing splicing impacts on the proteome.

Quick Start

IsoPepTracker provides four main modules for comprehensive peptide and alternative splicing analysis:

• Canonical Protein Isoform Analysis: Analyze canonical peptides across protein isoforms

• Novel mRNA Isoform Analysis: Identify and characterize novel mRNA isoforms using peptides

• Peptide Search: Search for specific peptides across all genes and protein isoforms in the database

• Alternative Splicing: Visualize and analyze peptide impact of alternative splicing events

Note

Performance Note for Large Genes

Most genes (e.g. TP53) load within seconds. Exceptionally large genes such as TTN, which contains over 300 exons, may require approximately 10 minutes to fully load due to the volume of transcript and peptide data.

Getting Started

• Introduction
  • A Shiny Application for Alternative Splicing Analysis and Peptide Mapping
  • Getting Started

Modules

• Canonical Protein Isoform Analysis
  • 1. Overview Analysis
  • 2. Events-Centric Analysis
  • 3. Isoform-Centric Analysis
  • Usage Workflow
• Novel mRNA Isoform Analysis
  • Key Features
  • Workflow
  • Output
• Peptide Search Module
  • Search Parameters
  • How to Use
  • Search Results
• Alternative Splicing Analysis Module
  • Supported Splicing Event Types
  • Input Support
  • Key Features
  • Workflow
  • Output

Resources

• Contact & Resources
  • Getting Help
  • Support Channels
  • Contributing
  • Citation
  • Development Team
  • System Requirements
  • Frequently Asked Questions

External Links

• Web Application

• Source Code

Indices and tables

• Index

• Module Index

• Search Page